Searchable abstracts of presentations at key conferences in endocrinology

ea0022oc6.1 | Bone | ECE2010

A proteomic approch to study parathyroid glands

Cetani Filomena , Giusti Laura , Ciregia Federica , Banti Chiara , Da Valle Ylenia , Donadio Elena , Lucacchini Antonio , Marcocci Claudio

The molecular basis of parathyroid tumorigenesis has increased greatly over the last years and the variety of described abnormalities suggests different genetic defects leading to dysfunction of parathyroid cells. Using a combined approach based on two-dimensional electrophoresis (2DE) and mass spectrometry (MS) we performed a comparative proteome analysis to examine the global changes of parathyroid adenoma tissues protein profile with respect to the normal parathyroid tissue...